To prevent DLP Endpoint Enforce from monitoring certain files, you need to add those files in the Tech Support Only section of the Endpoint Group Configuration in the Enterprise Manager. Bt default, the Endpoint currently ignores files with ".exe" and ".dll" extensions and also ignores files that start with "\\device\\","pipe\\".

As an example, one would need to enter the following in the Override Configuration under Tech Support Only section of the Endpoint Group configuration page:

<Advanced>
<FileIgnore>
<StartsWith>"partial path that you want to ignore"</StartsWith>
<StartsWith>root#</StartsWith>
<StartsWith>usb#</StartsWith>
<StartsWith>hid#</StartsWith>
<StartsWith>hdaudio#</StartsWith>
<StartsWith>\\device\\</StartsWith>
<StartsWith>\\systemroot\\</StartsWith>
<StartsWith>\\\\tsclient\\scard</StartsWith>
<StartsWith>pipe\\</StartsWith>
<StartsWith>global\\</StartsWith>
</FileIgnore>
</Advanced>

Few things to note here:

1) Endpoint will ignore any file that starts with the path, so if you open a Network share using the above option, then anything copied over to the share will NOT be monitored.

2) This setting is system wide, and will be applicable for ALL application running on the system.